Nusinersen in adult patients with 5q spinal muscular atrophy: A multicenter observational cohorts' study.

Juan Francisco Vázquez CostaMónica PovedanoAndrés E Nascimiento-OsorioAntonio Moreno EscribanoSolange Kapetanovic GarciaRaul DominguezJessica M ExpositoLaura GonzálezCarla MarcoJulita Medina CastilloNuria MuelasDaniel Natera de BenitoNancy Carolina Ñungo GarzónInmaculada Pitarch CastellanoTeresa SevillaDavid Hervás

Published in: European journal of neurology (2022)

Nusinersen treatment is associated with some improvements in adult SMA patients. Most severely affected patients with complex spines are probably those with the most unfavorable risk-benefit ratio.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
cross sectional
peritoneal dialysis
prognostic factors
clinical trial
young adults
smoking cessation
replacement therapy