Phase II Trial of Atezolizumab Combined With Carboplatin and Pemetrexed for Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer With Untreated Brain Metastases (Atezo-Brain, GECP17/05).
Ernest NadalDelvys Rodríguez-AbreuMarta SimóBartomeu MassutiOscar Juan-VidalGerardo HuidobroRafael López-CastroJavier De Castro CarpeñoAnna Estival GonzalezJoaquín MosqueraIvana G SullivanEnriqueta Felip FontAna BlascoMaria GuiradoEva PereiraNoelia VilariñoValentín NavarroJordi BrunaPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Atezolizumab plus carboplatin and pemetrexed demonstrates activity in patients with advanced nonsquamous NSCLC with untreated brain metastases with an acceptable safety profile.
Keyphrases
- brain metastases
- small cell lung cancer
- phase ii study
- open label
- phase iii
- resting state
- white matter
- functional connectivity
- advanced non small cell lung cancer
- placebo controlled
- locally advanced
- clinical trial
- randomized controlled trial
- multiple sclerosis
- cerebral ischemia
- squamous cell carcinoma
- study protocol
- double blind