Metformin Is Associated With Higher Relative Abundance of Mucin-Degrading Akkermansia muciniphila and Several Short-Chain Fatty Acid-Producing Microbiota in the Gut.
Jacobo de la Cuesta-ZuluagaNoel T MuellerVanessa Corrales-AgudeloEliana P Velásquez-MejíaJenny A CarmonaJosé M AbadJuan S EscobarPublished in: Diabetes care (2016)
Our results support the hypothesis that metformin shifts gut microbiota composition through the enrichment of mucin-degrading A. muciniphila as well as several SCFA-producing microbiota. Future studies are needed to determine if these shifts mediate metformin's glycemic and anti-inflammatory properties.