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Impact of body fat accumulation on metabolic dysfunction-associated fatty liver disease and nonalcoholic fatty liver disease in Japanese male young adults.

Takao MiwaCathelencia FrancisqueSatoko TajirikaTatsunori HanaiNanako ImamuraMiho AdachiRyo HoritaLynette J MenezesTakumi KawaguchiMasahito ShimizuMayumi Yamamoto
Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2023)
Our study revealed that fat accumulation plays a key role in the development of NAFLD and MAFLD in male young adults, even in nonobese individuals. The results could shed new light on the pathophysiology of NAFLD and MAFLD in young adults.
Keyphrases
  • young adults
  • childhood cancer
  • adipose tissue
  • fatty acid
  • oxidative stress
  • single cell
  • liver fibrosis