Levels of oxidative DNA damage are low in ex vivo engineered human limbal epithelial tissue.
Yolanda LorenzoKristiane Haug BergAmund RingvoldGoran PetrovskiMorten C MoeAndrew CollinsBjørn NicolaissenPublished in: Acta ophthalmologica (2018)
Our findings indicate low levels of oxidative stress and/or efficient DNA purine base damage repair in human limbal epithelium engineered in a medium with human serum as the single growth-promoting additive as well as in traditional medium with xenobiotics.