A multi-omics approach unravels metagenomic and metabolic alterations of a probiotic and synbiotic additive in rainbow trout (Oncorhynchus mykiss).

Jacob Agerbo Rasmussen Kasper Rømer Villumsen Madeleine Ernst Martin Hansen Torunn Forberg Shyam Gopalakrishnan Marcus Thomas Pius Gilbert Anders Miki Bojesen Karsten Kristiansen Morten Tønsberg Limborg

Published in: Microbiome (2022)

Our results demonstrate how the use of multi-omics to investigate complex host-microbiome interactions enable us to better evaluate the functional potential of probiotics compared to studies that only measure overall growth performance or that only characterise the microbial composition in intestinal environments. Video Abstract.

Keyphrases

single cell
microbial community
antibiotic resistance genes
case control
bacillus subtilis