Differential regulation of NPY and SP receptor expression in STRO-1+ve PDLSCs by inflammatory cytokines.

Lewis WinningIkhlas A El KarimGerard J LindenChristopher R IrwinSimon A KilloughFionnuala T Lundy

Published in: Journal of periodontal research (2021)

Expression of the neuropeptide Y Y1 receptor gene on STRO-1 +ve PDLSCs was sensitive to local inflammatory cytokines. Treatment of cells with neuropeptide Y was found to produce a modest enhanced osteogenic effect.

Keyphrases

induced apoptosis
poor prognosis
mesenchymal stem cells
cell cycle arrest
bone marrow
binding protein
genome wide
copy number
endoplasmic reticulum stress
oxidative stress
cell death
combination therapy
dna methylation
long non coding rna
genome wide identification