Neuroprotective effects of GPR68 against cerebral ischemia-reperfusion injury via the NF-κB/Hif-1α pathway.
Xianglong LiKaiguo XiaChuanhong ZhongXiangzhou ChenFubing YangLigang ChenJian You
Published in: Brain research bulletin (2024)
This study confirms that the GPR68/NF-κB/Hif-1α axis modulates apoptosis, inflammation, and oxidative stress in CIRI, indicating that GPR68 is a potential therapeutic target for CIRI.