Chronic Exposure to Normobaric Hypoxia Increases Testosterone Levels and Testosterone/Cortisol Ratio in Cyclists.

The aim of this study was to analyze the effects of the "live high, train low" method (LH-TL) and intermittent hypoxic training (IHT) on testosterone (T) and cortisol (C) levels in cyclists. Thirty cyclists participated in the experiment. The LH-TL group ( n = 10) was exposed to normobaric hypoxia (FiO 2 = 16.3%) for 11-12 h a day and trained in normoxia for 3 weeks. In the IHT group ( n = 10), participants followed the IHT routine three times a week for 3 weeks in normobaric hypoxia (FiO 2 = 16.3%). The control group (N; n = 10) followed the same training protocol in normoxia. The LH-TL training was found to significantly increase ( p < 0.05) T levels and the testosterone/cortisol (T/C) ratio during the experiment. The area under the curve (AUC) calculated for T levels over 4 weeks was significantly ( p < 0.05) higher in the LH-TL group, by 25.6%, compared to the N group. The results also indicated a significant correlation (r = 0.53; p < 0.05) between AUC for T levels over 4 weeks and ∆ values of hemoglobin (HGB) in the LH-TL group. Overall, the findings show that LH-TL training at a moderate simulated altitude contributes to an increase in T levels and T/C ratio in athletes, which is a beneficial change stimulating anabolic processes and erythropoiesis.