Distinct patterns of brain Fos expression in Carioca High- and Low-conditioned Freezing Rats.
Laura A LeónMarcus L BrandãoFernando P CardenasDiana ParraThomas E KraheAntonio Pedro Mello CruzJesús Landeira-FernándezPublished in: PloS one (2020)
Both CHF and CLF rats displayed Fos expression changes key regions of the anxiety brain circuitry. The two bidirectional lines exhibit different pattern of neural activation and inhibition with opposing influences on the PVN, the main structure involved in regulating the hypothalamic-pituitary-adrenal neuroendocrine responses observed in anxiety disorders.