Severe chronic kidney disease environment reduced calcium-sensing receptor expression in parathyroid glands of adenine-induced rats even without high phosphorus diet.

Taketo UchiyamaIchiro OhkidoAkio NakashimaYatsumu SaitoMasataka OkabeTakashi Yokoo

Published in: BMC nephrology (2020)

Our data suggest that the cause of the decreased PTG CaSR expression is the reduction in VDR and Gcm2 expression; Gcm2 may play a role in the onset and progression of SHPT.

Keyphrases

poor prognosis
chronic kidney disease
end stage renal disease
physical activity
weight loss
drug induced
high glucose
early onset
electronic health record
big data
machine learning
sewage sludge
data analysis