Intestinal stearoyl-CoA desaturase-1 regulates energy balance via alterations in bile acid homeostasis.

Natalie BurchatJeanine VidolaSarah PfreundschuhPriyanka SharmaDaniel RizzoloGrace L GuoHarini Sampath

Published in: bioRxiv : the preprint server for biology (2024)

Our results indicate that deletion of intestinal SCD1 has significant impacts on bile acid metabolism and whole-body energy balance, likely via activation of TGR5.

Keyphrases

fatty acid