Outcome study of the Pipeline Vantage Embolization Device (second version) in unruptured (and ruptured) aneurysms (PEDVU(R) study).

Thomas C Booth Ahmed Bassiouny Jeremy Lynch Hemant Sonwalkar Aaron BleakleyAhmed IqbalThais Soares Ciariancullo Minett Jonathon Buwanabala Ana Paula Narata Tufail Patankar Fathallah Ismail IslimNaga KandasamyParthiban BalasundaramSara SciaccaJuveria SiddiquiDaniel WalshChristos Tolias Ahilan Kailaya-VasanAmina A SultanMahmoud Abd El-Latif Alex MortimerAnand Sastry

Published in: Journal of neurointerventional surgery (2023)

For unruptured aneurysm treatment, the second PEDV version appears to have a superior efficacy and similar safety profile to previous-generation PEDs. These are acceptable outcomes in this pragmatic and non-industry-sponsored study. Analysis of ruptured aneurysm outcomes is limited by cohort size. Further prospective studies, particularly for ruptured aneurysms, are needed.

Keyphrases

coronary artery
subarachnoid hemorrhage
randomized controlled trial
clinical trial
middle cerebral artery
adipose tissue
skeletal muscle
psychometric properties