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Modern human changes in regulatory regions implicated in cortical development.

Juan A MorianoCedric Boeckx
Published in: BMC genomics (2020)
This study complements previous research focused on protein-coding changes distinguishing our species from Neanderthals/Denisovans and highlights chromatin regulation as a functional category so far overlooked in modern human evolution studies. We present a set of candidates that will help to illuminate the investigation of modern human-specific ontogenetic trajectories.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • pluripotent stem cells
  • gene expression
  • transcription factor
  • depressive symptoms
  • dna damage
  • dna methylation
  • amino acid