Effects of folate supplementation on recurrence and metabolic status of cervical intraepithelial neoplasia grade 2/3 in overweight and obese women: a randomized double-blind placebo-controlled trial.
Sima SabihiZahra VahedpoorSahar Saraf-BankMojgan NourianPublished in: European journal of clinical nutrition (2022)
In conclusion, folate supplementation for 12 weeks among overweight/obese women with CIN2/3 showed a non-significant decrease in its recurrence and had beneficial effects on insulin sensitivity, inflammation, and oxidative stress markers.
Keyphrases
- oxidative stress
- double blind
- high grade
- weight loss
- free survival
- placebo controlled
- clinical trial
- study protocol
- polycystic ovary syndrome
- adipose tissue
- metabolic syndrome
- dna damage
- type diabetes
- diabetic rats
- ischemia reperfusion injury
- induced apoptosis
- bariatric surgery
- weight gain
- randomized controlled trial
- obese patients
- insulin resistance
- skeletal muscle
- endoplasmic reticulum stress
- body mass index