Complement component 3 as biomarker of disease activity and cardiometabolic risk factor in rheumatoid arthritis and spondyloarthritis.

Iván Arias de la RosaPilar FontAlejandro Escudero-ContrerasMaría Dolores López-MontillaCarlos Pérez-SánchezMaría Carmen Ábalos-AguileraLourdes Ladehesa-PinedaAlejandro Ibáñez-CostaCarmen Torres-GranadosYolanda Jimenez-GomezAlejandra Patiño-TrivesMaría Luque-TévarMaría Carmen Castro-VillegasJerusalem Calvo-GutiérrezRafaela Ortega-CastroChary López-PedreraEduardo Collantes-EstévezNuria Barbarroja

Published in: Therapeutic advances in chronic disease (2020)

Complement C3 is associated with the concomitant increased prevalence of cardiometabolic risk factors in rheumatoid arthritis and spondyloarthritis. Thus, complement C3 should be considered a useful marker of insulin resistance and disease activity in these rheumatic disorders.

Keyphrases

disease activity
rheumatoid arthritis
risk factors
ankylosing spondylitis
rheumatoid arthritis patients
systemic lupus erythematosus
insulin resistance
juvenile idiopathic arthritis
interstitial lung disease
adipose tissue
type diabetes
metabolic syndrome
high fat diet
skeletal muscle
polycystic ovary syndrome