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Dysregulated expression of hypoxia-inducible factors augments myofibroblasts differentiation in idiopathic pulmonary fibrosis.

Arnoldo Aquino-GálvezGeorgina González-ÁvilaLaura Lorena Jiménez-SánchezHéctor Aquiles Maldonado-MartínezJosé CisnerosFernanda Toscano-MarquezManuel Castillejos-LópezLuz María Torres-EspíndolaRafael Velázquez-CruzVíctor Hugo Olivera RodríguezEdgar Flores-SotoHéctor Solís-ChagoyánCarlos CabelloJoaquín ZúñigaYair Romero
Published in: Respiratory research (2019)
This study lends further support to the involvement of hypoxia in the pathogenesis of IPF, and poses HIF-3α expression as a potential negative regulator of these phenomena.
Keyphrases
  • idiopathic pulmonary fibrosis
  • poor prognosis
  • endothelial cells
  • interstitial lung disease
  • rheumatoid arthritis
  • risk assessment