Performance of glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) biomarkers in predicting CT scan results and neurological outcomes in children with traumatic brain injury (BRAINI-2 paediatric study): protocol of a European prospective multicentre study.
Fleur LortonAlfonso LagaresJavier de la CruzOdile MéjanVladislav PavlovVincent SapinMaria Antonia PocaMarkus LehnerPeter BiberthalerAnne Chauviré-DrouardChristèle Gras-Le-GuenPauline Scherdelnull nullnull nullPublished in: BMJ open (2024)
NCT05413499.
Keyphrases
- traumatic brain injury
- computed tomography
- study protocol
- dual energy
- randomized controlled trial
- young adults
- intensive care unit
- image quality
- emergency department
- clinical trial
- small molecule
- contrast enhanced
- protein protein
- ionic liquid
- positron emission tomography
- neuropathic pain
- open label
- magnetic resonance imaging
- binding protein
- amino acid
- severe traumatic brain injury
- type diabetes
- double blind
- cerebral ischemia
- spinal cord injury
- skeletal muscle
- subarachnoid hemorrhage