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Successful olaparib desensitization using a novel one-day protocol.

Rongbo ZhuStephen WelchHannah Roberts
Published in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2020)
To our knowledge, this is the first reported case of successful olaparib desensitization using a novel 1-day desensitization protocol, and will contribute to drug allergy knowledge, in an area where robust data is lacking. This case demonstrates the important role for drug desensitization in patients with immediate hypersensitivity reactions to chemotherapeutic agents. Furthermore, as olaparib capsules are being phased out in favour of olaparib tablets, we provide a clear case that transitioning from capsule to tablet form did not cause a loss of tolerance.
Keyphrases
  • healthcare
  • randomized controlled trial
  • drug induced
  • electronic health record
  • big data
  • machine learning
  • adverse drug
  • deep learning
  • infectious diseases