Presence of Coronary Endothelial Dysfunction, Coronary Vasospasm, and Adenosine-Mediated Vasodilatory Disorders in Patients With Ischemia and Nonobstructive Coronary Arteries.
Rutger G T FeenstraCoen K M BoerhoutJanneke WoudstraCaitlin E M VinkMarianne E WittekoekGuus A de WaardYolande AppelmanEtto C EringaKoen M J MarquesRobbert J de WinterMarcel A M BeijkTim P van de HoefJan J PiekPublished in: Circulation. Cardiovascular interventions (2022)
Concomitant endothelial dysfunction was prevalent in the vast majority of patients with INOCA with inducible CAS and/or an impaired adenosine-mediated vasodilation. In patients with INOCA without inducible CAS and normal adenosine-mediated vasodilation, two-thirds had endothelial dysfunction. These results indicate the relevance to perform endothelial function testing in patients with INOCA in view of its therapeutic implication.