Genetically enhancing the expression of chemokine domain of CX3CL1 fails to prevent tau pathology in mouse models of tauopathy.
Shane M BemillerNicole M MaphisShane V FormicaGina N WilsonCrystal M MillerGuixiang XuOlga N Kokiko-CochranKi-Wook KimSteffen JungJudy L CannonSamuel D CrishAstrid E CardonaBruce T LambKiran BhaskarPublished in: Journal of neuroinflammation (2018)
Collectively, our data suggest that overexpression of only chemokine domain of CX3CL1 does not protect against tau pathology.