Poor Prognosis Biomolecular Factors Are Highly Frequent in Childhood Acute Leukemias From Oaxaca, Mexico.

Gerardo Juárez-AvendañoNuria Citlalli Luna-SilvaEuler Chargoy-VivaldoLaura Alicia Juárez-MartínezMayra Noemí Martínez-RangelNoemí Zárate-OrtizEdith Martínez-ValenciaBriceida López-MartínezRosana PelayoJuan Carlos Balandrán

Published in: Technology in cancer research & treatment (2021)

Our findings identify near 50% of patients with acute lymphoblastic leukemia at debut with high-risk translocations and poor prognosis in B-cell acute lymphoblastic leukemia as well as an unexpected increase of acute myeloid leukemia cases in young children, suggesting a molecular shift that support a higher incidence of poor prognosis cases in Oaxaca.

Keyphrases

poor prognosis
acute lymphoblastic leukemia
long non coding rna
allogeneic hematopoietic stem cell transplantation
acute myeloid leukemia
liver failure
risk factors
intensive care unit
drug induced
acute respiratory distress syndrome
childhood cancer