Angiotensin Receptor Blockers and the Risk of Suspected Drug-Induced Liver Injury: A Retrospective Cohort Study Using Electronic Health Record-Based Common Data Model in South Korea.

Hyunjoo KimNayeong SonDahee JeongMyungsik YooIn Young ChoiWona ChoiYeon Woong ChungSung Woo KoSeonjeong ByunSun ImDa Woon SimJewon SeoMin-Gyu KangJun Kyu LeeYoung-Gyun SeoHye-Ji AnYeesuk KimSungeu ChaeDae Won JunDong-Jin ChangSeong Geun KimSiyeon YiHyeon-Jong YangInho LeeHye Jung ParkJae-Hyun LeeBong Gi KimEunkyung Euni Lee

Published in: Drug safety (2024)

We found a significantly higher risk of suspected DILI in patients receiving azilsartan monotherapy compared with valsartan monotherapy. Our findings emphasize the utility of real-world evidence in advancing our understanding of adverse drug reactions in clinical practice.

Keyphrases

electronic health record
adverse drug
clinical practice
angiotensin converting enzyme
combination therapy
pulmonary embolism
clinical decision support
open label
drug induced
angiotensin ii
randomized controlled trial
clinical trial
deep learning
study protocol
big data