Alu element in the RNA binding motif protein, X-linked 2 (RBMX2) gene found to be linked to bipolar disorder.

Pia Laine William J RowellLars PaulinSteve KujawaDenise RatermanGeorge MayhewJennifer WendtDaniel L BurgessTimo PartonenTiina PaunioPetri AuvinenJenny M Ekholm

Published in: PloS one (2021)

Among the three genetically linked SVs, additional evidence supported the Alu element deletion in RBMX2 as the leading candidate for contributing directly to the disease development of BD type I in this extended family.

Keyphrases

bipolar disorder
major depressive disorder
binding protein
genome wide
copy number
protein protein
gene expression