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Discovering genes and microRNAs involved in human lung development unveils IGFBP3/miR-34a dynamics and their relevance for alveolar differentiation.

Melissa Acosta-PlasenciaJoan J CastellanoTania DíazYangyi HeRamón M MarradesAlfonso Navarro-Ródenas
Published in: Stem cell research & therapy (2024)
The IGFBP3/miR-34a axis restricts IGFBP3 expression in the embryonic undifferentiated lung epithelium, and the progressive downregulation of IGFBP3 during the pseudoglandular stage is required for alveolar differentiation.
Keyphrases
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  • gene expression