Immune Profile of BRAF-Mutated Metastatic Colorectal Tumors with Good Prognosis after Palliative Chemotherapy.

Jeong Eun Kim Gwanghun KimSang-Yeob KimHyungwoo ChoYeon-Mi RyuYong Sang HongSun Young KimTae Won Kim

Published in: Cancers (2022)

The clinical outcomes of unselected patients with BRAF-MT CRC were generally similar to those in previous studies. Based on the immune profile analysis, higher PD-L1 expression and CD8-positive cell infiltration were observed in BRAF-MT tumors with a good prognosis.

Keyphrases

wild type
metastatic colorectal cancer
squamous cell carcinoma
small cell lung cancer
single cell
cell therapy
palliative care
case control
advanced cancer
mesenchymal stem cells
rectal cancer