Cancer Treatment Using Different Shapes of Gold-Based Nanomaterials in Combination with Conventional Physical Techniques.
Simona TarantinoAnna Paola CaricatoRosaria RinaldiCaterina CapomollaValeria De MatteisPublished in: Pharmaceutics (2023)
The conventional methods of cancer treatment and diagnosis, such as radiotherapy, chemotherapy, and computed tomography, have developed a great deal. However, the effectiveness of such methods is limited to the possible failure or collateral effects on the patients. In recent years, nanoscale materials have been studied in the field of medical physics to develop increasingly efficient methods to treat diseases. Gold nanoparticles (AuNPs), thanks to their unique physicochemical and optical properties, were introduced to medicine to promote highly effective treatments. Several studies have confirmed the advantages of AuNPs such as their biocompatibility and the possibility to tune their shapes and sizes or modify their surfaces using different chemical compounds. In this review, the main properties of AuNPs are analyzed, with particular focus on star-shaped AuNPs. In addition, the main methods of tumor treatment and diagnosis involving AuNPs are reviewed.
Keyphrases
- gold nanoparticles
- computed tomography
- end stage renal disease
- randomized controlled trial
- ejection fraction
- systematic review
- healthcare
- locally advanced
- early stage
- newly diagnosed
- mental health
- radiation therapy
- positron emission tomography
- prognostic factors
- squamous cell carcinoma
- magnetic resonance
- peritoneal dialysis
- mass spectrometry
- patient reported outcomes
- rectal cancer
- case control
- image quality
- silver nanoparticles
- single molecule