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Circulating receptor activator of nuclear factor kappa-B ligand (RANKL) levels predict response to immune checkpoint inhibitors in advanced non-small cell lung cancer (NSCLC).

Michele IulianiSonia SimonettiLeonardo CristofaniSilvia CavaliereAlessio CortelliniMarco RussanoBruno VincenziGiuseppe ToniniDaniele SantiniFrancesco Pantano
Published in: Journal for immunotherapy of cancer (2024)
These results highlight the prognostic and predictive value of RANKL specifically in patients with high PDL1 expression.
Keyphrases
  • nuclear factor
  • advanced non small cell lung cancer
  • toll like receptor
  • epidermal growth factor receptor
  • poor prognosis
  • binding protein
  • tyrosine kinase
  • inflammatory response
  • long non coding rna
  • immune response