Patritumab with Cetuximab plus Platinum-Containing Therapy in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: An Open-Label, Phase Ib Study.
Magnus T DillonLorna GroveKate L NewboldHeather ShawNicholas F BrownJeanne MendellShuquan ChenRobert A BeckmanAnne JenningsMarivic RicamaraJonathan GreenbergMartin ForsterKevin J HarringtonPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)
Patritumab (18 mg/kg loading dose, 9 mg/kg maintenance dose) plus cetuximab/platinum was tolerable, active in SCCHN, and selected as the phase II dose regimen.