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Tretinoin (0.05% cream vs. 5% peel) for photoaging and field cancerization of the forearms: randomized, evaluator-blinded, clinical trial.

J M SumitaH A MiotJ L M SoaresA C P RaminelliS M PereiraM M OgawaF R PicosseL R S GuadanhimM M S S EnokiharaG R LeonardiE Bagatin
Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2018)
Tretinoin as a cream 0.05% or peeling (5%) is safe and effective for the treatment of moderate photoaging and forearm field cancerization. The cream was superior in improving ultrasonographic parameters of ageing. Peeling was shown a superior performance in the stabilization of field cancerization.
Keyphrases
  • clinical trial
  • double blind
  • open label
  • phase ii
  • phase iii
  • study protocol
  • randomized controlled trial
  • replacement therapy
  • optical coherence tomography