Cardiac automaticity is modulated by IKACh in sinoatrial node during pregnancy.

Valérie LongGracia El GebeilyÉlisabeth LeblancMarwa SenhadjiCéline Fiset

Published in: Cardiovascular research (2024)

IKACh function and expression are decreased in the mouse SAN during pregnancy, strongly suggesting that, in addition to other electrical remodeling of the SAN, reduced IKACh also plays an important role in the pregnancy-induced increased HR.

Keyphrases

poor prognosis
high glucose
diabetic rats
lymph node
left ventricular
preterm birth
drug induced
binding protein
pregnancy outcomes
long non coding rna
oxidative stress
atrial fibrillation
stress induced