Preparation of Structurally Diverse Compounds from the Natural Product Lycorine.
Sarah Z TaskerAmanda E CowferPaul J HergenrotherPublished in: Organic letters (2018)
The synthesis of a 52-member compound collection from the natural product lycorine is reported, highlighted by divergent cross-coupling and substitution strategies and an unusual ring rearrangement induced by reaction with aryne intermediates.