Transcriptomic Analysis Reveals an Altered Hcy Metabolism in the Stria Vascularis of the Pendred Syndrome Mouse Model.

Wenyue XueYuxin TianYuanping XiongFeng LiuYanmei Feng Zhengnong Chen Dongzhen Yu Shan-Kai Yin

Published in: Neural plasticity (2021)

The altered expression of Bhmt results in a dramatic change in multiple biochemical reactions and a disruption of nutrient homeostasis in the endolymph which may contribute to hearing loss of Slc26a4 knockout mouse.

Keyphrases

mouse model
hearing loss
poor prognosis
case report
binding protein
long non coding rna