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Eosinophilic Fasciitis Following Checkpoint Inhibitor Therapy: Four Cases and a Review of Literature.

Karmela Kim ChanCynthia MagroAlexander N ShoushtariCharles M RudinVeronica M RotembergAnthony RossiCecilia LezcanoJohn A CarrinoDavid FernandezMichael A PostowArlyn ApolloMario E LacoutureAnne R Bass
Published in: The oncologist (2019)
It is important for clinicians to recognize that eosinophilic fasciitis is a potential immune-related adverse event (irAE) as a consequence of immune checkpoint inhibitor therapy. The presentation is quite stereotypical; the diagnosis can be made by imaging in the absence of a full-thickness skin biopsy. Early intervention is important to limit morbidity. This irAE may be a good prognostic sign among patients with melanoma.
Keyphrases
  • randomized controlled trial
  • dna damage
  • palliative care
  • cell cycle
  • optical coherence tomography
  • soft tissue
  • ultrasound guided
  • bone marrow
  • oxidative stress
  • mass spectrometry
  • cell therapy
  • fine needle aspiration