Direct oral anticoagulant versus antiplatelet therapy following transcatheter aortic valve replacement in patients without prior or concurrent indication for anticoagulation: A meta-analysis of randomized studies.
Matheus Jose Barbosa MoreiraNatália Araújo do Amaral PeixotoOfonime Chantal Udoma-UdofaSílvia L S de AraújoShirley Katherine Tinajero EnriquezPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2022)
In this meta-analysis of randomized studies comparing DOACs to antiplatelet therapy after TAVR in patients without a concomitant indication for anticoagulation, DOACs were associated with a lower incidence of valve thrombosis and a higher rate of all-cause mortality, driven by an increase in noncardiac causes of death.
Keyphrases
- antiplatelet therapy
- transcatheter aortic valve replacement
- end stage renal disease
- aortic valve
- ejection fraction
- acute coronary syndrome
- aortic stenosis
- systematic review
- percutaneous coronary intervention
- newly diagnosed
- chronic kidney disease
- atrial fibrillation
- venous thromboembolism
- squamous cell carcinoma
- peritoneal dialysis
- radiation therapy
- heart failure
- randomized controlled trial
- mitral valve
- coronary artery disease
- patient reported outcomes
- left ventricular