Efficacy and Safety of P2Y12 Inhibitor Monotherapy After Complex PCI: A Collaborative Systematic Review and Meta-Analysis.
Johny NicolasGeorge DangasMauro ChiaritoCarlo Andrea PivatoAlessandro SpiritDavide CaoGennaro GiustinoFrans J BeerkensAnton CamajBirgit VogelSamantha SartoriKo YamamotoTakeshi KimuraByeong-Keuk KimUsman BaberRoxana MehranPublished in: European heart journal. Cardiovascular pharmacotherapy (2022)
As compared with a standard DAPT, a 1-3-month DAPT regimen followed by P2Y12 inhibitor monotherapy reduced bleeding complications after C-PCI without increasing the risk of ischemic events.
Keyphrases
- antiplatelet therapy
- percutaneous coronary intervention
- acute coronary syndrome
- combination therapy
- atrial fibrillation
- coronary artery disease
- acute myocardial infarction
- st segment elevation myocardial infarction
- open label
- st elevation myocardial infarction
- coronary artery bypass grafting
- heart failure
- randomized controlled trial
- clinical trial
- brain injury
- cerebral ischemia
- study protocol
- subarachnoid hemorrhage