Tethered spinal cord tension assessed via ultrasound elastography in computational and intraoperative human studies.
Max J KerenskyAbhijit PaulDenis RoutkevitchAndrew M HershKelley M Kempski LeadinghamA Daniel DavidarBrendan F JudyJoshua PunnooseAutumn WilliamsAvisha KumarKurt LehnerBeth SmithJennifer K SonJavad R AzadiHimanshu ShekharKarla P Mercado-ShekharNitish V ThakorNicholas TheodoreAmir ManbachiPublished in: Communications medicine (2024)
This study presents a physical, clinical metric of spinal cord tension. Strong agreement among computational, cadaveric, and clinical studies demonstrates the utility of ultrasound-induced SWV for quantitative intraoperative feedback. This technology is positioned to enhance tethered cord diagnosis, treatment, and postoperative monitoring as it differentiates stretched from healthy cords.
Keyphrases
- spinal cord
- patients undergoing
- magnetic resonance imaging
- endothelial cells
- spinal cord injury
- ultrasound guided
- neuropathic pain
- high glucose
- physical activity
- mental health
- diabetic rats
- contrast enhanced ultrasound
- high resolution
- induced pluripotent stem cells
- pluripotent stem cells
- oxidative stress
- drug induced
- combination therapy