Expression and Regulatory Network Analysis of BICC1 for Aged Sca-1-Positive Bone Narrow Mesenchymal Stem Cells.
Zhongshuang LiuChuntao OuSiyu XiangQi XieShuangjiang CheDandi ZhangLingna MengZiqi LiuGuohong ZhangYing WangYun HuangWenjing ZhangYongqiang DengPublished in: Disease markers (2022)
As a genetic gene that affects bone mineral density, BICC1 may be a new target for clinical treatment of senile osteoporosis by influencing osteogenic differentiation of BMSCs through EGFR-related signaling. However, the application of the results requires support from more experimental data.
Keyphrases
- bone mineral density
- network analysis
- postmenopausal women
- mesenchymal stem cells
- body composition
- genome wide
- small cell lung cancer
- copy number
- poor prognosis
- transcription factor
- epidermal growth factor receptor
- tyrosine kinase
- umbilical cord
- bone marrow
- big data
- stem cells
- binding protein
- combination therapy
- cell therapy
- artificial intelligence
- data analysis
- genome wide identification
- replacement therapy
- genome wide analysis
- deep learning