Cardiovascular System in COVID-19: Simply a Viewer or a Leading Actor?
Filiberto Fausto MottolaNicoletta VerdeRiccardo RicciolinoMarco Di Di MauroMarco Giuseppe MigliaccioVincenzo CarforaGiorgio SpinielloNicola Coppolanull Vanvitelli Covid-GroupPublished in: Life (Basel, Switzerland) (2020)
As of January 2020, a new pandemic has spread from Wuhan and caused thousands of deaths worldwide. Several studies have observed a relationship between coronavirus disease (COVID-19) infection and the cardiovascular system with the appearance of myocardial damage, myocarditis, pericarditis, heart failure and various arrhythmic manifestations, as well as an increase in thromboembolic risk. Cardiovascular manifestations have been highlighted especially in older and more fragile patients and in those with multiple cardiovascular risk factors such as cancer, diabetes, obesity and hypertension. In this review, we will examine the cardiac involvement associated with SARS-CoV-2 infection, focusing on the pathophysiological mechanism underlying manifestations and their clinical implication, taking into account the main scientific papers published to date.
Keyphrases
- coronavirus disease
- cardiovascular risk factors
- respiratory syndrome coronavirus
- heart failure
- left ventricular
- end stage renal disease
- type diabetes
- cardiovascular disease
- sars cov
- metabolic syndrome
- chronic kidney disease
- ejection fraction
- newly diagnosed
- blood pressure
- insulin resistance
- papillary thyroid
- atrial fibrillation
- weight loss
- patient reported outcomes
- peritoneal dialysis
- randomized controlled trial
- skeletal muscle
- squamous cell carcinoma
- adipose tissue
- systematic review
- acute heart failure
- body mass index
- lymph node metastasis
- young adults
- weight gain
- squamous cell
- patient reported