Treating Bipolar Depression with Esketamine: Safety and Effectiveness data from a naturalistic multicentric study on Esketamine in Bipolar versus Unipolar Treatment-Resistant Depression.

Giovanni MartinottiBernardo Dell'OssoGiorgio Di LorenzoGiuseppe MainaAlessandro BertolinoMassimo ClericiStefano BarlatiGianluca RossoMarco Di NicolaMatteo MarcatiliGiacomo D'AndreaClara CavallottoStefania ChiappiniSergio De FilippisGiuseppe NicolòPasquale De FazioIleana AndriolaRaffaella ZanardiDomenica NuciforaStefania Di MauroRoberta BassettiMauro PettorrusoRoger S McIntyreStefano L SensiMassimo di GiannantonioAntonio Vitanull null

Published in: Bipolar disorders (2023)

Our results supported the effectiveness and tolerability of esketamine in a real-world population of subjects with B-TRD. The low risk of manic switch in B-TRD patients confirmed the safety of this treatment.

Keyphrases

bipolar disorder
randomized controlled trial
end stage renal disease
depressive symptoms
systematic review
chronic kidney disease
sleep quality
electronic health record
open label
machine learning
physical activity
replacement therapy
patient reported
data analysis