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Efficacy and safety of sofosbuvir/velpatasvir versus the standard of care in adults hospitalized with COVID-19: a single-centre, randomized controlled trial.

Babak SayadReza KhodarahmiFarid NajafiRonak MiladiZeinab Mohseni AfsharFeizollah MansouriZohreh RahimiMaria ShirvaniMehdi SalimiSiavash VaziriAlireza JanbakhshFatemeh Khosravi ShadmaniArezoo BozorgomidMohammad Hossein ZamanianMandana Afsharian
Published in: The Journal of antimicrobial chemotherapy (2021)
Although treatment with SOF/VEL was safe, adding SOF/VEL to the standard of care did not improve the clinical status or reduce mortality in patients with moderate to severe COVID-19. However, larger randomized clinical trials including more parameters are needed for accurate estimation of the efficacy of SOF/VEL.
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