Brain free fatty acid uptake is elevated in morbid obesity, and is irreversible 6 months after bariatric surgery: A positron emission tomography study.
Eleni RebelosJussi HirvonenMarco BucciLaura PekkarinenMikko NymanJarna C HannukainenPatricia IozzoPaulina SalminenLauri NummenmaaEleuterio FerranniniPirjo NuutilaPublished in: Diabetes, obesity & metabolism (2020)
BFAU is increased in morbidly obese compared with lean subjects, and is unchanged 6 months after bariatric surgery. Baseline BFAU predicts worse plasma glucose levels at follow-up, supporting the notion that the brain participates in the control of whole-body homeostasis.
Keyphrases
- positron emission tomography
- bariatric surgery
- computed tomography
- weight loss
- obese patients
- metabolic syndrome
- resting state
- fatty acid
- white matter
- type diabetes
- insulin resistance
- pet ct
- functional connectivity
- pet imaging
- adipose tissue
- cerebral ischemia
- weight gain
- body mass index
- blood glucose
- multiple sclerosis
- brain injury