Determination of pyrrolizidine alkaloids in tea and honey with automated SPE clean-up and ultra-performance liquid chromatography/tandem mass spectrometry.
Oliver KeuthH U HumpfPeter FürstPublished in: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (2021)
For routine analytical purpose a method based on a combination of automated solid-phase extraction (SPE) clean-up and detection by Ultra-Performance Liquid Chromatography/Tandem Mass Spectrometry (UPLC-MS/MS) was developed for the determination of pyrrolizidine alkaloids (PA) in various food commodities. In this survey, honey, tea and herbal infusion samples from local retailers collected in 2012-2015 were obtained and analysed for their PA content. PA concentrations were found in 30% of the honey samples and in 42% of the tea and herbal infusion samples with levels up to 595 µg/kg. The survey included 17 individual PA, and their sum is also reported for each sample.
Keyphrases
- solid phase extraction
- liquid chromatography tandem mass spectrometry
- simultaneous determination
- high performance liquid chromatography
- molecularly imprinted
- liquid chromatography
- ms ms
- tandem mass spectrometry
- gas chromatography mass spectrometry
- ultra high performance liquid chromatography
- machine learning
- deep learning
- high throughput
- low dose
- cross sectional
- gas chromatography
- high resolution
- mass spectrometry
- high resolution mass spectrometry
- clinical practice
- quantum dots
- human health