Physiologically-based pharmacokinetic modeling to inform combination dosing regimens of ceftaroline and daptomycin in special populations.
Frederico Severino MartinsJosé Eduardo Severino MartinsPatricia SeverinoPieter AnnaertSherwin K B SyPublished in: British journal of clinical pharmacology (2023)
Our work illustrates how PBPK modeling can inform appropriate dosing of adult and pediatric patients and thereby enable prediction of target attainment in the patients during multi-therapies.