Pieter Annaert (P Annaert)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 54

Top Venues

Drug metabolism and disposition: the biological fate of chemicals

Pharmaceutics

BMJ paediatrics open

Cancers

KU Leuven Research and Development (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

KU Leuven Research and Development Oct 01 1994 - Oct 30 1998

Belgium

PHD :: Pharmaceutical and Pharmacological Sciences

Publications

Agustos Cetin Ozbey, Janneke Keemink, Bjoern Wagner, Alessandra Pugliano, Stephan Krähenbühl, Pieter Annaert, Stephen Fowler, Neil Parrott, Kenichi Umehara
Physiologically based pharmacokinetic modeling to predict the impact of liver cirrhosis on glucuronidation via UGT1A4 & UGT2B7/2B4 - a case study with midazolam. Drug metabolism and disposition: the biological fate of chemicals (2024)
Agustos Cetin Ozbey, Janneke Keemink, Bjoern Wagner, Alessandra Pugliano, Stephan Krähenbühl, Pieter Annaert, Stephen Fowler, Neil Parrott, Kenichi Umehara
Physiologically Based Pharmacokinetic Modeling to Predict the Impact of Liver Cirrhosis on Glucuronidation via UGT1A4 and UGT2B7/2B4-A Case Study with Midazolam. Drug metabolism and disposition: the biological fate of chemicals 52 (7) (2024)
Marina-Stefania Stroe, Miao-Chan Huang, Pieter Annaert, Karen Leys, Anne Smits, Karel Allegaert, Lieselotte Van Bockstal, Allan Valenzuela, Miriam Ayuso, Chris Van Ginneken, Steven J Van Cruchten
Drug Disposition in Neonatal Göttingen Minipigs: Exploring Effects of Perinatal Asphyxia and Therapeutic Hypothermia. Drug metabolism and disposition: the biological fate of chemicals 52 (8) (2024)
Martje Van Neste, Nina Nauwelaerts, Michael Ceulemans, Kristel Van Calsteren, An Eerdekens, Pieter Annaert, Karel Allegaert, Anne Smits
Determining the exposure of maternal medicines through breastfeeding: the UmbrelLACT study protocol-a contribution from the ConcePTION project. BMJ paediatrics open 8 (1) (2024)
Martje Van Neste, Nina Nauwelaerts, Michael Ceulemans, Kristel Van Calsteren, An Eerdekens, Pieter Annaert, Karel Allegaert, Anne Smits
Determining the exposure of maternal medicines through breastfeeding: the UmbrelLACT study protocol-a contribution from the ConcePTION project. BMJ paediatrics open 8 (1) (2024)
Martje Van Neste, Nina Nauwelaerts, Michael Ceulemans, Kristel Van Calsteren, An Eerdekens, Pieter Annaert, Karel Allegaert, Anne Smits
Determining the exposure of maternal medicines through breastfeeding: the UmbrelLACT study protocol-a contribution from the ConcePTION project. BMJ paediatrics open 8 (1) (2024)
Martje Van Neste, Nina Nauwelaerts, Michael Ceulemans, Kristel Van Calsteren, An Eerdekens, Pieter Annaert, Karel Allegaert, Anne Smits
Determining the exposure of maternal medicines through breastfeeding: the UmbrelLACT study protocol-a contribution from the ConcePTION project. BMJ paediatrics open 8 (1) (2024)
Karel Allegaert, Anne Smits, Pieter Annaert
Interdisciplinary Collaboration on Real World Data to Close the Knowledge Gap: A Reflection on "De Sutter et al. Predicting Volume of Distribution in Neonates: Performance of Physiologically Based Pharmacokinetic Modelling". Pharmaceutics 16 (1) (2024)
Anaëlle Monfort, Evelina Cardoso, Chin Bin Eap, Nicolas Ansermot, Séverine Crettol, Céline J Fischer Fumeaux, Myriam Bickle Graz, Mathilde Morisod Harari, Etienne Weisskopf, Peggy Gandia, Karel Allegaert, Pieter Annaert, Hedvig Nordeng, Jean-Michel Hascoët, Olivier Claris, Manuella Epiney, Ema Ferreira, Grégoire Leclair, Chantal Csajka, Alice Panchaud, Monia Guidi, null null
A population pharmacokinetic model for sertraline in women during the perinatal period-A contribution from the ConcePTION project. British journal of clinical pharmacology (2024)
Sarinj Fattah, Abhijit Babaji Shinde, Myriam Baes, Karel Allegaert, Patrick Augustijns, Pieter Annaert
Ontogeny of hepatic Organic Cation Transporter-1 in rat and human . Drug metabolism and disposition: the biological fate of chemicals (2024)
Agustos Cetin Ozbey, Janneke Keemink, Bjoern Wagner, Alessandra Pugliano, Stephan Krähenbühl, Pieter Annaert, Stephen Fowler, Neil Parrott, Kenichi Umehara
Physiologically Based Pharmacokinetic Modeling to Predict the Impact of Liver Cirrhosis on Glucuronidation via UGT1A4 and UGT2B7/2B4-A Case Study with Midazolam. Drug metabolism and disposition: the biological fate of chemicals 52 (7) (2024)
Karel Allegaert, Anne Smits, Pieter Annaert
Interdisciplinary Collaboration on Real World Data to Close the Knowledge Gap: A Reflection on "De Sutter et al. Predicting Volume of Distribution in Neonates: Performance of Physiologically Based Pharmacokinetic Modelling". Pharmaceutics 16 (1) (2024)
Karel Allegaert, Anne Smits, Pieter Annaert
Interdisciplinary Collaboration on Real World Data to Close the Knowledge Gap: A Reflection on "De Sutter et al. Predicting Volume of Distribution in Neonates: Performance of Physiologically Based Pharmacokinetic Modelling". Pharmaceutics 16 (1) (2024)
Martje Van Neste, Nina Nauwelaerts, Michael Ceulemans, Kristel Van Calsteren, An Eerdekens, Pieter Annaert, Karel Allegaert, Anne Smits
Determining the exposure of maternal medicines through breastfeeding: the UmbrelLACT study protocol-a contribution from the ConcePTION project. BMJ paediatrics open 8 (1) (2024)
Agustos Cetin Ozbey, Janneke Keemink, Bjoern Wagner, Alessandra Pugliano, Stephan Krähenbühl, Pieter Annaert, Stephen Fowler, Neil Parrott, Kenichi Umehara
Physiologically Based Pharmacokinetic Modeling to Predict the Impact of Liver Cirrhosis on Glucuronidation via UGT1A4 and UGT2B7/2B4-A Case Study with Midazolam. Drug metabolism and disposition: the biological fate of chemicals 52 (7) (2024)
Marina-Stefania Stroe, Miao-Chan Huang, Pieter Annaert, Karen Leys, Anne Smits, Karel Allegaert, Lieselotte Van Bockstal, Allan Valenzuela, Miriam Ayuso, Chris Van Ginneken, Steven Van Cruchten
Drug disposition in neonatal Göttingen Minipigs: Exploring Effects of Perinatal Asphyxia and Therapeutic Hypothermia . Drug metabolism and disposition: the biological fate of chemicals (2024)
Frederico Severino Martins, José Eduardo Severino Martins, Patricia Severino, Pieter Annaert, Sherwin K B Sy
Physiologically-based pharmacokinetic modeling to inform combination dosing regimens of ceftaroline and daptomycin in special populations. British journal of clinical pharmacology (2023)
Martje Van Neste, Annick Bogaerts, Nina Nauwelaerts, Julia Macente, Anne Smits, Pieter Annaert, Karel Allegaert
Challenges Related to Acquisition of Physiological Data for Physiologically Based Pharmacokinetic (PBPK) Models in Postpartum, Lactating Women and Breastfed Infants-A Contribution from the ConcePTION Project. Pharmaceutics 15 (11) (2023)
Nina Nauwelaerts, Julia Macente, Neel Deferm, Rodolfo Hernandes Bonan, Miao-Chan Huang, Martje Van Neste, David Bibi, Justine Badee, Frederico Severino Martins, Anne Smits, Karel Allegaert, Thomas Bouillon, Pieter Annaert
Generic Workflow to Predict Medicine Concentrations in Human Milk Using Physiologically-Based Pharmacokinetic (PBPK) Modelling-A Contribution from the ConcePTION Project. Pharmaceutics 15 (5) (2023)
Karen Leys, Marina-Stefania Stroe, Pieter Annaert, Steven J Van Cruchten, Sebastien Christian Carpentier, Karel Allegaert, Anne Smits
Pharmacokinetics during therapeutic hypothermia in neonates: from pathophysiology to translational knowledge and physiologically-based pharmacokinetic (PBPK) modeling. Expert opinion on drug metabolism & toxicology (2023)
Evelina Cardoso, Monia Guidi, Nina Nauwelaerts, Hedvig Marie Egeland Nordeng, Marie Teil, Karel Allegaert, Anne Smits, Peggy Gandia, Andrea Edginton, Shinya Ito, Pieter Annaert, Alice Panchaud
Safety of medicines during breastfeeding - from case report to modeling : A contribution from the ConcePTION project. Expert opinion on drug metabolism & toxicology (2023)
Agustos Cetin Ozbey, Stephen Fowler, Karen Leys, Pieter Annaert, Kenichi Umehara, Neil Parrott
PBPK Modelling for Drugs Cleared by Non-CYP Enzymes: State-of-the-Art and Future Perspectives. Drug metabolism and disposition: the biological fate of chemicals (2023)
Agustos C Ozbey, Fabio Bachmann, Urs Duthaler, Pieter Annaert, Stephen Fowler, Kenichi Umehara, Neil Parrott, Stephan Krähenbühl
Dose adjustment in patients with liver cirrhosis - comparison of two different modeling approaches. Clinical pharmacology and therapeutics (2023)
Getahun Befirdu Abza, Jemal Hussien Ahmed, Abdu Adem Yesufe, Edom Seife, Mengistu Erkie, Isabel Spriet, Legese Chelkeba, Pieter Annaert
Clinicopathological Features and Survival of Patients with Hepatocellular Carcinoma in Ethiopia: A Multicenter Study. Cancers 15 (1) (2022)
Karel Allegaert, Mohammad Yaseen Abbasi, Pieter Annaert, Olusola Olafuyi
Current and future physiologically based pharmacokinetic (PBPK) modeling approaches to optimize pharmacotherapy in preterm neonates. Expert opinion on drug metabolism & toxicology 18 (5) (2022)
Getahun Befirdu Abza, Jemal Hussien Ahmed, Abdu Adem Yesufe, Edom Seife, Mengistu Erkie, Isabel Spriet, Legese Chelkeba, Pieter Annaert
Clinicopathological Features and Survival of Patients with Hepatocellular Carcinoma in Ethiopia: A Multicenter Study. Cancers 15 (1) (2022)
Getahun Befirdu Abza, Jemal Hussien Ahmed, Abdu Adem Yesufe, Edom Seife, Mengistu Erkie, Isabel Spriet, Legese Chelkeba, Pieter Annaert
Clinicopathological Features and Survival of Patients with Hepatocellular Carcinoma in Ethiopia: A Multicenter Study. Cancers 15 (1) (2022)
Axelle Cooreman, Anne Caufriez, Andrés Tabernilla, Raf Van Campenhout, Kaat Leroy, Prashant Kadam, Julen Sanz Serrano, Bruna Dos Santos Rodrigues, Pieter Annaert, Mathieu Vinken
Effects of Drugs Formerly Proposed for COVID-19 Treatment on Connexin43 Hemichannels. International journal of molecular sciences 23 (9) (2022)
Matthias Gijsen, Omar Elkayal, Pieter Annaert, Ruth Van Daele, Philippe Meersseman, Yves Debaveye, Joost Wauters, Erwin Dreesen, Isabel Spriet
Meropenem Target Attainment and Population Pharmacokinetics in Critically Ill Septic Patients with Preserved or Increased Renal Function. Infection and drug resistance 15 (2022)
Getahun Befirdu Abza, Jemal Hussien Ahmed, Abdu Adem Yesufe, Edom Seife, Mengistu Erkie, Isabel Spriet, Legese Chelkeba, Pieter Annaert
Clinicopathological Features and Survival of Patients with Hepatocellular Carcinoma in Ethiopia: A Multicenter Study. Cancers 15 (1) (2022)
Elin Ngo, Olav Spigset, Angela Lupattelli, Alice Panchaud, Pieter Annaert, Karel Allegaert, Hedvig Nordeng
Antihistamine use during breastfeeding with focus on breast milk transfer and safety in humans: A systematic literature review. Basic & clinical pharmacology & toxicology (2021)
Noor Borloo, Anne Smits, Liesbeth Thewissen, Pieter Annaert, Karel Allegaert
Creatinine Trends and Patterns in Neonates Undergoing Whole Body Hypothermia: A Systematic Review. Children (Basel, Switzerland) 8 (6) (2021)
Matthias Gijsen, Erwin Dreesen, Ruth Van Daele, Pieter Annaert, Yves Debaveye, Joost Wauters, Isabel Spriet
Pharmacokinetic/Pharmacodynamic Target Attainment Based on Measured versus Predicted Unbound Ceftriaxone Concentrations in Critically Ill Patients with Pneumonia: An Observational Cohort Study. Antibiotics (Basel, Switzerland) 10 (5) (2021)
Sabrina De Winter, Reinier van Hest, Erwin Dreesen, Pieter Annaert, Joost Wauters, Wouter Meersseman, Nele Van den Eede, Stefanie Desmet, Sandra Verelst, Peter Vanbrabant, Willy Peetermans, Isabel Spriet
Quantification and Explanation of the Variability of First-Dose Amikacin Concentrations in Critically Ill Patients Admitted to the Emergency Department: A Population Pharmacokinetic Analysis. European journal of drug metabolism and pharmacokinetics 46 (5) (2021)
Karel Allegaert, Thomas Salaets, Robert M Ward, Pieter Annaert, Anne Smits
QTc Intervals Are Prolonged in Late Preterm and Term Neonates during Therapeutic Hypothermia but Normalize Afterwards. Children (Basel, Switzerland) 8 (12) (2021)
Matthias Gijsen, Erwin Dreesen, Pieter Annaert, Johan Nicolai, Yves Debaveye, Joost Wauters, Isabel Spriet
Meropenem Pharmacokinetics and Target Attainment in Critically Ill Patients Are Not Affected by Extracorporeal Membrane Oxygenation: A Matched Cohort Analysis. Microorganisms 9 (6) (2021)
Chiara Bernardini, Debora La Mantia, Roberta Salaroli, Augusta Zannoni, Nina Nauwelaerts, Neel Deferm, Domenico Ventrella, Maria Laura Bacci, Giuseppe Sarli, Michele Bouisset-Leonard, Pieter Annaert, Monica Forni
Development of a Pig Mammary Epithelial Cell Culture Model as a Non-Clinical Tool for Studying Epithelial Barrier-A Contribution from the IMI-ConcePTION Project. Animals : an open access journal from MDPI 11 (7) (2021)
B D van Groen, Johan Nicolai, A C Kuik, S Van Cruchten, E van Peer, A Smits, S Schmidt, S N de Wildt, K Allegaert, L De Schaepdrijver, Pieter Annaert, J Badée
Ontogeny of Hepatic Transporters and Drug-Metabolizing Enzymes in Humans and in Nonclinical Species. Pharmacological reviews 73 (2) (2021)
Matthias Gijsen, Benjamin Filtjens, Pieter Annaert, Yeghig Armoudjian, Yves Debaveye, Joost Wauters, Peter Slaets, Isabel Spriet
Meropenem Stability in Human Plasma at -20 °C: Detailed Assessment of Degradation. Antibiotics (Basel, Switzerland) 10 (4) (2021)
Marlly Guarin, Annelii Ny, Noémie De Croze, Jan Maes, Marc Léonard, Pieter Annaert, Peter A M de Witte
Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis. Pharmaceuticals (Basel, Switzerland) 14 (6) (2021)
Alanah Pieters, Eva Gijbels, Bruno Cogliati, Pieter Annaert, Lindsey Devisscher, Mathieu Vinken
Biomarkers of cholestasis. Biomarkers in medicine 15 (6) (2021)
Ruth Van Daele, Joost Wauters, Pieter De Cock, Franky Buyle, John Leys, Pieter Van Brantegem, Matthias Gijsen, Pieter Annaert, Yves Debaveye, Katrien Lagrou, Willy E Peetermans, Roger J Brüggemann, Isabel Spriet
Concomitant Treatment with Voriconazole and Flucloxacillin: A Combination to Avoid. Antibiotics (Basel, Switzerland) 10 (9) (2021)
Suzanne J F Kaptein, Sofie Jacobs, Lana Langendries, Laura Seldeslachts, Sebastiaan Ter Horst, Laurens Liesenborghs, Bart Hens, Valentijn Vergote, Elisabeth Heylen, Karine Barthelemy, Elke Maas, Carolien De Keyzer, Lindsey Bervoets, Jasper Rymenants, Tina Van Buyten, Xin Zhang, Rana Abdelnabi, Juanita Pang, Rachel Williams, Hendrik-Jan Thibaut, Kai Dallmeier, Robbert Boudewijns, Jens Wouters, Patrick Augustijns, Nick Verougstraete, Christopher J Cawthorne, Judith Breuer, Caroline Solas, Birgit Weynand, Pieter Annaert, Isabel Spriet, Greetje Vande Velde, Johan Neyts, Joana Rocha-Pereira, Leen Delang
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity. Proceedings of the National Academy of Sciences of the United States of America 117 (43) (2020)
Miriam Ayuso, Laura Buyssens, Marina Stroe, Allan Valenzuela, Karel Allegaert, Anne Smits, Pieter Annaert, Antonius Mulder, Sebastien Carpentier, Chris Van Ginneken, Steven J Van Cruchten
The Neonatal and Juvenile Pig in Pediatric Drug Discovery and Development. Pharmaceutics 13 (1) (2020)
John N Van den Anker, Susan McCune, Pieter Annaert, Gerri R Baer, Yeruk Mulugeta, Ramy Abdelrahman, Kunyi Wu, Kevin M Krudys, Jeffrey Fisher, William Slikker, Connie Chen, Gilbert J Burckart, Karel Allegaert
Approaches to Dose Finding in Neonates, Illustrating the Variability between Neonatal Drug Development Programs. Pharmaceutics 12 (7) (2020)
Bing Qi, Matthias Gijsen, Pieter Van Brantegem, Tom De Vocht, Neel Deferm, Getahun Befirdu Abza, Nina Nauwelaerts, Joost Wauters, Isabel Spriet, Pieter Annaert
Quantitative determination of colistin A/B and colistin methanesulfonate in biological samples using hydrophilic interaction chromatography tandem mass spectrometry. Drug testing and analysis 12 (8) (2020)
Axelle Cooreman, Raf Van Campenhout, Sara Crespo Yanguas, Eva Gijbels, Kaat Leroy, Alanah Pieters, Andrés Tabernilla, Pieter Van Brantegem, Pieter Annaert, Bruno Cogliati, Mathieu Vinken
Cholestasis Differentially Affects Liver Connexins. International journal of molecular sciences 21 (18) (2020)
Bing Qi, Johan Nicolai, Anne Smits, Tom De Vocht, Neel Deferm, Pieter Van Brantegem, Karel Allegaert, Pieter Annaert
A sensitive liquid chromatography method for analysis of propofol in small volumes of neonatal blood. Journal of clinical pharmacy and therapeutics 45 (1) (2019)
Neel Deferm, Tom De Vocht, Bing Qi, Pieter Van Brantegem, Eva Gijbels, Mathieu Vinken, Peter A M de Witte, Thomas Bouillon, Pieter Annaert
Current insights in the complexities underlying drug-induced cholestasis. Critical reviews in toxicology 49 (6) (2019)
Arianna Giusti, Xuan-Bac Nguyen, Stanislav Kislyuk, Mélanie Mignot, Cecilia Ranieri, Johan Nicolai, Marlies Oorts, Xiao Wu, Pieter Annaert, Noémie De Croze, Marc Léonard, Annelii Ny, Deirdre Cabooter, Peter A M de Witte
Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos. International journal of molecular sciences 20 (7) (2019)
Nico Holmstock, Marlies Oorts, Jan Snoeys, Pieter Annaert
MRP2 Inhibition by HIV Protease Inhibitors in Rat and Human Hepatocytes: A Quantitative Confocal Microscopy Study. Drug metabolism and disposition: the biological fate of chemicals 46 (5) (2018)
Francesca Maria Russo, Alexandra Benachi, Tim VAN Mieghem, Jan De Hoon, Kristel Van Calsteren, Pieter Annaert, Jean-Marc Tréluyer, Karel Allegaert, Jan A Deprest
Antenatal sildenafil administration to prevent pulmonary hypertension in congenital diaphragmatic hernia (SToP-PH): study protocol for a phase I/IIb placenta transfer and safety study. Trials 19 (1) (2018)
Sarinj Fattah, Abhijit Babaji Shinde, Maja Matic, Myriam Baes, Ron H N van Schaik, Karel Allegaert, Celine Parmentier, Lysiane Richert, Patrick Augustijns, Pieter Annaert
Inter-Subject Variability in OCT1 Activity in 27 Batches of Cryopreserved Human Hepatocytes and Association with OCT1 mRNA Expression and Genotype. Pharmaceutical research 34 (6) (2017)
T Vanhove, Pieter Annaert, D Lambrechts, D R J Kuypers
Effect of ABCB1 diplotype on tacrolimus disposition in renal recipients depends on CYP3A5 and CYP3A4 genotype. The pharmacogenomics journal 17 (6) (2016)

Pieter Annaert.css-eqlu8i{font-size:small;padding-left:4px;} (P Annaert)

Publication Activity (10 Years)

Top Topics

Top Venues

Pieter Annaert (P Annaert)