Histological demonstration of BSEP/ABCB11 inhibition in transient neonatal cholestasis: a case report.

Anna BaghdasaryanLisa Ofner-ZiegenfußCarolin LacknerPeter FickertBernhard ReschNicholas Mark MorrisAndrea Deutschmann

Published in: BMC pediatrics (2020)

This report demonstrates for the first time a close association between the prolonged cholestasis in infancy and impaired BSEP expression on the hepatocyte canalicular membrane in a heterozygous carrier of newly-identified ABCB11 variant.

Keyphrases

drug induced
liver injury
poor prognosis
early onset
weight gain
cerebral ischemia
binding protein
long non coding rna
brain injury
blood brain barrier
subarachnoid hemorrhage