Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy.

Mina ShahriyariMd Rezaul IslamSadman M SakibMalte RinnAnastasia RikaDennis KrügerLalit KauraniVerena GisaMandy WinterhoffHarithaa AnandakumarOrr ShomroniMatthias SchmidtGabriela SalinasAndreas UngerWolfgang A LinkeJana ZschüntzschJens SchmidtRhonda Bassel-DubyEric N OlsonAndré FischerWolfram-Hubertus ZimmermannMalte Tiburcy

Published in: Journal of cachexia, sarcopenia and muscle (2022)

We introduce human muscle models with canonical properties of bona fide skeletal muscle in vivo to study muscle development, maturation, disease and repair.

Keyphrases

skeletal muscle
endothelial cells
insulin resistance
induced pluripotent stem cells
stem cells
pluripotent stem cells