Functional Characterization of lncRNA152 as an Angiogenesis-Inhibiting Tumor Suppressor in Triple-Negative Breast Cancers.
Dae-Seok KimCristel V CamachoRohit SetlemKangsan KimSrinivas MalladiTim Y HouTulip NanduShrikanth S GadadW Lee KrausPublished in: Molecular cancer research : MCR (2022)
This study identifies lncRNA152 as an angiogenesis-inhibiting tumor suppressor that attenuates the aggressive cancer-related phenotypes found in TNBC by upregulating the expression of the tumor suppressor RBM47. As such, lncRNA152 may serve as a biomarker to track aggressiveness of breast cancer, as well as therapeutic target for treating TNBC.