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Genetic Risk for Alzheimer's Disease Alters Perceived Executive Dysfunction in Cognitively Healthy Middle-Aged and Older Adults.

Sarah A EvansElizabeth R PaitelRiya BhasinKristy A Nielson
Published in: Journal of Alzheimer's disease reports (2024)
Utilizing an approach that integrates self-evaluation of executive functioning with objective neurocognitive assessment may help identify the earliest signs of impending cognitive decline, particularly in those with genetic risk for AD. Such an approach could sensitively determine those most prone to future cognitive decline prior to symptom onset, when interventions could be most effective.
Keyphrases
  • cognitive decline
  • mild cognitive impairment
  • physical activity
  • genome wide
  • working memory
  • oxidative stress
  • social support
  • copy number
  • bipolar disorder
  • dna methylation
  • current status