The Expressions of TSLP, IL-33, and IL-17A in Monocyte Derived Dendritic Cells from Asthma and COPD Patients are Related to Epithelial-Macrophage Interactions.
Magdalena Paplińska-GorycaPaulina Misiukiewicz-StępieńMalgorzata ProboszczPatrycja Nejman-GryzKatarzyna GorskaRafal KrenkePublished in: Cells (2020)
TSLP, IL-33, and IL-17A expression in moDCs are differently regulated by epithelium in asthma, COPD, and healthy subjects. These complex cell-cell interactions may impact airway inflammation and be an important factor in the pathobiology of asthma and COPD.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- single cell
- cystic fibrosis
- air pollution
- cell therapy
- end stage renal disease
- ejection fraction
- allergic rhinitis
- newly diagnosed
- poor prognosis
- stem cells
- adipose tissue
- chronic kidney disease
- prognostic factors
- endothelial cells
- patient reported outcomes
- patient reported